Birth Control Pill Poses a Serious Health Risk to Women With a Common Condition

The examine found that, when in comparison with non-users who had been regular weight, the danger of venous thromboembolism was 12-fold increased in chubby ladies and 24-fold increased in overweight ladies.

Mixed contraception capsule tremendously will increase the danger of blood clots in overweight ladies. 

Based on a paper lately revealed in ESC Coronary heart Failure, a journal of the European Society of Cardiology, overweight ladies who use oral contraceptives containing estrogen and progestin have a 24-fold elevated danger of venous thromboembolism (VTE) in comparison with non-obese ladies who don’t use the medication.

Examine writer Professor Giuseppe Rosano of the IRCCS San Raffaele Pisana, Rome, Italy stated: “It’s effectively established that each weight problems and estrogen-containing contraceptives are danger elements for VTE. Regardless of this, overweight ladies proceed to obtain these medication. The scientific proof signifies that weight problems and mixed oral contraceptives have a synergistic impact on VTE danger and this ought to be thought of in prescribing selections. Progestin-only merchandise, together with drugs, intrauterine units, or implants are a safer various to the mixed capsule in ladies carrying extra weight.”

This evaluation article highlights the newest analysis on the person results of weight problems and contraceptives, in addition to the mixed affect of those elements, on the danger of VTE and affords scientific suggestions. VTE refers to a blood clot in a vein and encompasses two doubtlessly deadly situations: deep venous thrombosis and pulmonary embolism.

Based on the World Well being Group, the proportion of grownup ladies who’re overweight nearly quadrupled between 1975 and 2016. The danger of VTE grows progressively with physique mass index (BMI), and it’s greater than double in overweight ladies in comparison with non-obese ladies. Weight problems has the best impact on VTE ladies underneath 40, who’ve a five-fold higher danger in comparison with non-obese ladies.

Professor Rosano famous: “The significantly excessive danger in overweight ladies underneath 40 is vital since it’s at this age that many search contraception.”

Mixed oral contraceptives are related to an elevated chance of VTE, with customers having a three- to seven-fold elevated chance of VTE in contrast with non-users. In distinction, progestin-only merchandise aren’t related to an elevated danger of VTE.

The mixture of chubby/weight problems and the usage of mixed oral contraceptives potentiates the chance of blood clots in ladies of reproductive age. For instance, a big population-based examine discovered that being chubby and overweight was related to 1.7-fold and a pair of.4-fold elevated dangers of VTE, respectively. Nonetheless, in mixed capsule customers, the danger of VTE was 12-fold increased in chubby ladies and 24-fold increased in overweight ladies – in comparison with normal-weight non-users.

Professor Rosano stated: “Overweight ladies taking contraceptives are susceptible to VTE and may take steps to restrict their different predisposing elements for heart problems, for instance by quitting smoking and rising their bodily exercise ranges.”

Reference: “Weight problems and contraceptive use: affect on cardiovascular danger” by Giuseppe M.C. Rosano, Maria Angeles Rodriguez-Martinez, Ilaria Spoletini and Pedro Antonio Regidor, 14 September 2022, ESC Coronary heart Failure.
DOI: 10.1002/ehf2.14104